University Otago
Founded in 1869, the University of Otago is New Zealand’s oldest university, ranked in the top 1% globally by QS World University Rankings. It boasts a 5 Stars Plus rating for its facilities, teaching, and inclusiveness. The university has four academic divisions: Humanities, Health Sciences, Sciences, and the Otago Business School, with campuses in Dunedin, Christchurch, Wellington, Invercargill, and Auckland. Otago enrols around 20,000 students and employs over 5,600 staff. It is a member of the Matariki Network of Universities, emphasising research excellence and global collaboration. The university’s extensive library system and robust IT services support its research and academic endeavours.
Work in m2M
UoO will be involved in designing the optimal bio-printing strategy through understanding the interconnections of different cell types (T3.1, T3.2): UoO have extensive expertise in bioprinting of osteochondral tissues, and have pioneered bottom-up, 3D bioassembly strategies to generate fibre-reinforced osteochondral models consisting of chondrogenic and osteogenic cell-laden hydrogel spheroids, as well as to control spatial delivery of oxygen to tissue engineered constructs. Within m2M we will contribute our 3D spheroid bioassembly models as well as provide our unique visible-light activated bioinks to consortia partners for evaluating controlled spatial delivery of growth factors and oxygen (D3.4). This will complement developing automated 3D bioassembly strategies contributing to scale-up manufacturing processes.
Researchers involved
Host Institutions/Labs
Past Publications
- Lim et al. Fundamentals and applications of photocrosslinking in bioprinting. Chemical Reviews. 120(19). (2020).
- Norberg et al. Bioassembly of hemoglobin-loaded photopolymerizable spheroids alleviates hypoxia-induced cell death. Biofabrication (2024).
- Murphy et al. Next evolution in organ-scale biofabrication: bioresin design for high-resolution vat polymerization. Advanced Materials 34 (20). (2022).
- Cui et al. 3D bioassembly of cell-instructive chondrogenic & osteogenic hydrogel microspheres containing allogeneic stem cells for hybrid biofabrication of osteochondral constructs. Biofabrication. 14, 034101. (2022).
- Lindberg et al. Probing Multicellular Tissue Fusion of Cocultured Spheroids – A 3D-Bioassembly Model. Advanced Science. 8(22), 2103320. (2021).
